Reacciones adversas a fármacos
Introduction: Adverse Drugs Reactions (ADR) can seriously affect health and are a frequent medical consultation cause. Sometimes can even go unnoticed if you do not take account of them. To evaluate knowledge and value that the medical team gives to the issue is fundamental in avoid morbidity...
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| Publicado en: | Revista Médica Universitaria |
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| Autores principales: | , , , , , |
| Materias: | |
| Acceso en línea: | https://bdigital.uncu.edu.ar/fichas.php?idobjeto=11039 |
| Sumario: | Introduction:
Adverse Drugs Reactions (ADR) can seriously
affect health and are a frequent medical
consultation cause. Sometimes can even go
unnoticed if you do not take account of them. To
evaluate knowledge and value that the medical
team gives to the issue is fundamental in avoid
morbidity and mortality of the ADR.
Objectives:
To determine the level of knowledge of ADR in
the medical team. Reflect on the practice about
the ADR.
Material and methods:
Descriptive cross-sectional study through a selfadministered,
anonymous and validated survey
with closed true / false answer questions on ADR
of amiodarone, acenocoumarol, enalapril,
furosemide, salbutamol, clonazepam and
acetylsalicylic acid. The survey had 51 options for
the drugs mentioned. It was consulted about
pharmacological training, reading and thinking in
ADR prior to prescription, as well as, experiences
on the subject.
Staff doctors (SD), resident doctors (RD) and 6th
year medicine students (S) were included.
Statistical analysis: measures of central tendency,
scatter measures and Fisher\'s exact test. It was
considered significant p <0.05.
Outcomes:
107 people were surveyed; 85% were medical
doctors (60.4% RD, 39.6% SD) and 15% S. 58.9%
were women; average age: 31.3 years. 96%
studied pharmacology as a curricular activity
during their training. In the previous 6 months,
81.3% had read pharmacology and 16% had done
some course about it. At prescribing, 54%
thought ALWAYS about ADR, 6.54% report that
NEVER read ADR before prescribing and 27.1%
made it ALWAYS. 32% answered that they have
NEVER had patients with serious ADR; 43% 1 to 3
TIMES and 25% MORE THAN 3 TIMES. About ADR
in frequently used drugs, SD and RD answered
correctly in 74% each one. Students answered
correctly at 64%. About drugs, surveyed people
responded correctly at enalapril n 60 (56.07%),
acetylsalicylic acid n 57 (53.21%), prednisone n 54
(50.46), amiodarone n 21 (19.62%), salbutamol n
13 (12.14%), piperacillin tazobactam n 12
(11.21%), clonazepam n 12 (11.21%), furosemide
n 3 (2.8%), and acenocoumarol n 1 (0.93%). From
the comparative analysis between SD and RD, the
ALWAYS response in ADR was more frequent in
the first ones with SL (p = 0.08). We did not find
differences in training or reading on ADR before
prescribing between both groups.
Conclusion:
54% ALWAYS thought about ADR at prescribing
and only 27 referred to read ALWAYS this topic
before an indication. The drug that showed less
knowledge about was acenocoumarol and the
one that showed best knowledge about was
enalapril. The level of pharmacological
instruction, even in elementary drugs, in public or
private medical care system, is low. That is why is
more pharmacovigilance is to be implemented in
order to prevent ADR, as well as to make the
health team aware of the importance of this
problem. |
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