Osteonecrosis mandibular por uso de agentes antirresortivos

The antiresorptive agents-related osteoecrosis of the jaws (ARONJ) is a severe complication in patients receiving medications such as bisphosphonates, denosumab, or antiangiogens. Bisphosphonates and other antiresorptives, such as denosumab, are potent inhibitors of osteoclast function and osteocl...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Revista de la Facultad de Odontología
Autores principales: Palazzolo, Yanina, Pezzutti, Mariana, Vega, Cristina, Viadana, Julieta
Materias:
Acceso en línea:https://bdigital.uncu.edu.ar/fichas.php?idobjeto=16434
Descripción
Sumario:The antiresorptive agents-related osteoecrosis of the jaws (ARONJ) is a severe complication in patients receiving medications such as bisphosphonates, denosumab, or antiangiogens. Bisphosphonates and other antiresorptives, such as denosumab, are potent inhibitors of osteoclast function and osteoclast-mediated bone resorption. They are used effectively to reduce the bone resorption process and improve the quality of life of patients with osteoporosis, malignant osteolytic diseases and other bone lesions such as Paget’s disease or osteogenesis imperfecta 1, 6 We will present a clinical case of a 64-year-old patient, with a history of administration of zolendronate and denosumab, who presents bone exposure in the post-exodontic socket of 1 year of evolution.