Bacteriemias en Mayores de 65 años

Objectives: To evaluate clinical and bacteriological parameters and morbimortality in patients older than 65 years old with bacteremia (Group A), and to compare with patients younger than 65 years old (Group B), hospitalized in an Internal Medicine Service.- Material and Methods: In a protocoliz...

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Publicado en:Revista Médica Universitaria
Autores principales: Attorri, Silvia, Carena, José Alberto, Curti, Ana, Dapás, Juan, De Schutter, Emiliano, Mosso, Marcelo, Salomón, Susana Elsa
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Acceso en línea:https://bdigital.uncu.edu.ar/fichas.php?idobjeto=2745
descriptores_str_mv
Ancianos
Bacteriemia
Datos estadísticos
Infecciones bacterianas
Mendoza (Argentina)
Morbilidad
Morbimortalidad
Mortalidad
Pacientes hospitalizados
Pacientes internos
Pacientes mayores de 65 años
Septicemia
todos_str_mv 1221
2735
HospLagClinMed
HospLagClinMed
HospLagClinMed
HospLagClinMed
spa
UNCuyo FCM Dto. Medicina Interna
UNCuyo FCM Dto. Medicina Interna
UNCuyo.FCM.Infec
autor_str_mv Attorri, Silvia
Carena, José Alberto
Curti, Ana
Dapás, Juan
De Schutter, Emiliano
Mosso, Marcelo
Salomón, Susana Elsa
titulo_str_mv Bacteriemias en Mayores de 65 años
disciplina_str_mv Ciencias médicas
description_str_mv Objectives: To evaluate clinical and bacteriological parameters and morbimortality in patients older than 65 years old with bacteremia (Group A), and to compare with patients younger than 65 years old (Group B), hospitalized in an Internal Medicine Service.- Material and Methods: In a protocolized, descriptive and observational study from year 1989 through 2006 we studied patients with two or more positive blood cultures. Data was analized with Epi Info 6.4. Results: 668 bacteremias were identified: 258 (38.6%) in A and 410 (61.4%) in B. The mean age was 74.2 years (SD+7.01) and 47.2 years (SD+13.7) respectively. There were no differences in the mean hospital stay: 19.1 (SD+17.07) in A vs 19.9 days (SD+18.1) in B, neither in nosocomial acquisition (10.7 vs 44%). The pulmonary (31 vs 21.2%)(p<0.008) and urinary source (27 vs 18.8%)(p=0.017), arterial hypotension (40.8 vs 32.2%)(p=0.03), olyguria (41.7 vs 30.9%)(p=0.005) and encephalopathy (54.5 vs 39.4%)(p=0.00014) were more frequent in A. Fever >38°C was more common in B (9 0.9 vs 83.8%)(p=0.0068). Gram negative bacilli bacteremia were most common in A (46 vs 37%)(p>0.01). mainly with A. baumani (9.16 vs 4.6%) and E. coli (54.1 vs 42.7%)(p>0.05), and in B was S. aureus (39.39 vs 24.63)(p=0.01). There were no diferences between S. pneumoniae bacteremia:13.17 in A and 15.36% in B. Septic shock (33.9 vs 22.4%) and new organ failures (31.1 vs 20.1%) occurred mainly in A (p>0.001). In hospital mortality was 34.49% in A and 23.41% in B (p=0.018). Conclusions: Bacteremias in elderly hospitalized patients compared to those occurred in younger patients were significantly characterized by predominance of pulmonary and urinary source; arterial hypotension, olyguria and encephalopathy; gram negative bacilli bacteremia, mainly A. baumani and E. coli; more frequent development of septic shock; less frequency of fever>38°C and S.Aureus bacteremia and to significantly higher mortality.
Objetivos: Evaluar parámetros clínicos, bacteriológicos y morbimortalidad en pacientes mayores de 65 años con bacteriemia (Grupo A) y compararlos con aquellas ocurridas en menores de 65 años (grupo B) hospitalizados en un servicio de clínica médica. Material y métodos: Estudio protocolizado, descriptivo y observacional, desde 1989-2006. Criterios de inclusión: dos o más hemocultivos positivos. Análisis estadístico con Epi Info 6.4 . Resultados: Se identificaron 668 bacteriemias: 258 (38,6%) en A y 410 (61,4%) en B. La edad media fue de 74,2 años (DS±7.01) y de 47,2 años (DS±13.7) respectivamente. No hubo diferencias en la permanencia media: 19,1 días (DS±17.07) en A y 19,9 (DS±18,1) en B, ni en el origen nosocomial (40,7 vs 44%). Los focos pulmonar (31 vs 21,2%)(p<0,008) y urinario (27 vs 18,8%)(p=0.017) fue más frecuentes en A. La fiebre >de 38 ºC fue menos frecuente en A (83,8 vs 90,9%)(p=0.0068), mientras que la hipotensión arterial (40,8 vs 32,2%)(p=0.03), oliguria (41,7 vs 30,9%)(p=0.005) y encefalopatía (54,5 vs 39,4%)(p=0.00014) fueron mas comunes en A. Los bacilos gram negativos predominaron en A (46 vs 37%)(p<0.01) con diferencias entre A.baumani (9,16 vs 4,6%) y E.coli (54,1 vs 42,7%)(p<0.05) y en B fueron más frecuentes por S.aureus MS (34.39 vs 24,63)(p=0.01). El shock séptico (33,9 vs 22,4%) y nuevas insuficiencias de órganos (31,1 vs 20,1%) prevalecieron en A (p<0,001). La mortalidad fue de 34,49% para A y de 23,41% para B (p=0,018) Conclusiones: Las bacteriemias en pacientes internados mayores de 65 años comparadas con las ocurridas en pacientes. de menor edad, se caracterizaron significativamente por tener predominio del foco pulmonar y urinario, de hipotensión arterial, oliguria y encefalopatía, de bacteriemia por BGN, principalmente A. baumanii y E. coli; mayor desarrollo de shock séptico, menor frecuencia de fiebre >38°C y de bacteriemia por MSS A, y significativa mayor mortalidad.
object_type_str_mv Textual: Revistas
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container_title Revista Médica Universitaria
journal_title_str Revista Médica Universitaria
journal_id_str r-1221
container_issue Revista Médica Universitaria
container_volume Vol. 4, no. 3
journal_issue_str Vol. 4, no. 3
tipo_str textuales
type_str_mv Articulos
title_full Bacteriemias en Mayores de 65 años
title_fullStr Bacteriemias en Mayores de 65 años
Bacteriemias en Mayores de 65 años
title_full_unstemmed Bacteriemias en Mayores de 65 años
Bacteriemias en Mayores de 65 años
description Objectives: To evaluate clinical and bacteriological parameters and morbimortality in patients older than 65 years old with bacteremia (Group A), and to compare with patients younger than 65 years old (Group B), hospitalized in an Internal Medicine Service.- Material and Methods: In a protocolized, descriptive and observational study from year 1989 through 2006 we studied patients with two or more positive blood cultures. Data was analized with Epi Info 6.4. Results: 668 bacteremias were identified: 258 (38.6%) in A and 410 (61.4%) in B. The mean age was 74.2 years (SD+7.01) and 47.2 years (SD+13.7) respectively. There were no differences in the mean hospital stay: 19.1 (SD+17.07) in A vs 19.9 days (SD+18.1) in B, neither in nosocomial acquisition (10.7 vs 44%). The pulmonary (31 vs 21.2%)(p<0.008) and urinary source (27 vs 18.8%)(p=0.017), arterial hypotension (40.8 vs 32.2%)(p=0.03), olyguria (41.7 vs 30.9%)(p=0.005) and encephalopathy (54.5 vs 39.4%)(p=0.00014) were more frequent in A. Fever >38°C was more common in B (9 0.9 vs 83.8%)(p=0.0068). Gram negative bacilli bacteremia were most common in A (46 vs 37%)(p>0.01). mainly with A. baumani (9.16 vs 4.6%) and E. coli (54.1 vs 42.7%)(p>0.05), and in B was S. aureus (39.39 vs 24.63)(p=0.01). There were no diferences between S. pneumoniae bacteremia:13.17 in A and 15.36% in B. Septic shock (33.9 vs 22.4%) and new organ failures (31.1 vs 20.1%) occurred mainly in A (p>0.001). In hospital mortality was 34.49% in A and 23.41% in B (p=0.018). Conclusions: Bacteremias in elderly hospitalized patients compared to those occurred in younger patients were significantly characterized by predominance of pulmonary and urinary source; arterial hypotension, olyguria and encephalopathy; gram negative bacilli bacteremia, mainly A. baumani and E. coli; more frequent development of septic shock; less frequency of fever>38°C and S.Aureus bacteremia and to significantly higher mortality.
dependencia_str_mv Facultad de Ciencias Médicas
title Bacteriemias en Mayores de 65 años
spellingShingle Bacteriemias en Mayores de 65 años
Ancianos
Bacteriemia
Datos estadísticos
Infecciones bacterianas
Mendoza (Argentina)
Morbilidad
Morbimortalidad
Mortalidad
Pacientes hospitalizados
Pacientes internos
Pacientes mayores de 65 años
Septicemia
Attorri, Silvia
Carena, José Alberto
Curti, Ana
Dapás, Juan
De Schutter, Emiliano
Mosso, Marcelo
Salomón, Susana Elsa
topic Ancianos
Bacteriemia
Datos estadísticos
Infecciones bacterianas
Mendoza (Argentina)
Morbilidad
Morbimortalidad
Mortalidad
Pacientes hospitalizados
Pacientes internos
Pacientes mayores de 65 años
Septicemia
topic_facet Ancianos
Bacteriemia
Datos estadísticos
Infecciones bacterianas
Mendoza (Argentina)
Morbilidad
Morbimortalidad
Mortalidad
Pacientes hospitalizados
Pacientes internos
Pacientes mayores de 65 años
Septicemia
author Attorri, Silvia
Carena, José Alberto
Curti, Ana
Dapás, Juan
De Schutter, Emiliano
Mosso, Marcelo
Salomón, Susana Elsa
author_facet Attorri, Silvia
Carena, José Alberto
Curti, Ana
Dapás, Juan
De Schutter, Emiliano
Mosso, Marcelo
Salomón, Susana Elsa
title_sort Bacteriemias en Mayores de 65 años
title_short Bacteriemias en Mayores de 65 años
url https://bdigital.uncu.edu.ar/fichas.php?idobjeto=2745
estado_str 3
building Biblioteca Digital
filtrotop_str Biblioteca Digital
collection Artículo de Revista
institution Sistema Integrado de Documentación
indexed_str 2023-04-25 00:38
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