Adipocitoquinas y síndrome metabólico
Cardiovascular disease is the leading cause of mortality in western countries. Metabolic syndrome (MS), characterized by hyperlipidemia, hypertension, obesity and hyperglycemia, is a significant risk factor for cardiovascular disease. Visceral adipose tissue play a key role in the development of me...
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| Publicado en: | Revista Médica Universitaria |
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| Autores principales: | , , |
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| Acceso en línea: | https://bdigital.uncu.edu.ar/fichas.php?idobjeto=4178 |
| Sumario: | Cardiovascular disease is the leading cause of mortality in western countries.
Metabolic syndrome (MS), characterized by hyperlipidemia, hypertension, obesity and hyperglycemia, is a significant risk factor for cardiovascular disease. Visceral adipose tissue play a key role in the development of metabolic syndrome since this tissue secrets a variety of bioactive substances named adipokines or adipocytokines such as leptin, resistin, adiponectin, tumor necrosis factor alfa (TNFa), and visfatin. Visfatin has been described recently and its role in cardiovascular disease is controversial and has not yet been fully elucidated. Studies in human and animal experimental models suggest that visfatin would have a key role in the pathologies associates with cardiovascular disease. This review is focused in the role of visfatin as well as the main dipocytokines with cardiovascular disease and metabolic syndrome.
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