Adipocitoquinas y síndrome metabólico
Cardiovascular disease is the leading cause of mortality in western countries. Metabolic syndrome (MS), characterized by hyperlipidemia, hypertension, obesity and hyperglycemia, is a significant risk factor for cardiovascular disease. Visceral adipose tissue play a key role in the development of me...
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Publicado en: | Revista Médica Universitaria |
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Acceso en línea: | https://bdigital.uncu.edu.ar/fichas.php?idobjeto=4178 |
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Adipocitoquinas Adipocytokines Adiponectina Adipose tissue Cardiovascular diseases Diabetes Enfermedades cardiovasculares Factores de riesgo Leptina Mendoza (Argentina) Metabolic syndrome Obesidad Organización Mundial de la Salud Resistina Síndrome metabólico Tejido adiposo Visfatin Visfatina |
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1221 4168 spa UNCuyo_FCM_AFP UNCuyo_FCM_AFP UNCuyo_FCM_AFP |
titulo_str_mv |
Adipocitoquinas y síndrome metabólico |
description_str_mv |
Cardiovascular disease is the leading cause of mortality in western countries.
Metabolic syndrome (MS), characterized by hyperlipidemia, hypertension, obesity and hyperglycemia, is a significant risk factor for cardiovascular disease. Visceral adipose tissue play a key role in the development of metabolic syndrome since this tissue secrets a variety of bioactive substances named adipokines or adipocytokines such as leptin, resistin, adiponectin, tumor necrosis factor alfa (TNFa), and visfatin. Visfatin has been described recently and its role in cardiovascular disease is controversial and has not yet been fully elucidated. Studies in human and animal experimental models suggest that visfatin would have a key role in the pathologies associates with cardiovascular disease. This review is focused in the role of visfatin as well as the main dipocytokines with cardiovascular disease and metabolic syndrome.
La enfermedad cardiovascular es la primera causa de morbi-mortalidad en los países industrializados. El síndrome metabólico, caracterizado por hipertensión, dislipidemia, obesidad e hiperglucemia, constituye el principal factor de riesgo para la enfermedad cardiovascular. El tejido adiposo visceral juega un papel fundamental en este proceso, dado que secreta una variedad de sustancias biológicamente activas denominadas adipoquinas o adipocitoquinas, tales como leptina, resistina, adiponectina, factor de necrosis tumoral alfa (TNFa), y visfatina entre otras. La visfatina es una citoquina descubierta recientemente y su rol en la enfermedad cardiovascular es controversial y aún no ha sido completamente dilucidado. Estudios realizados en humanos y en modelos experimentales en animales sugieren que la visfatina tendría un papel muy importante en las patologías asociadas a la enfermedad cardiovascular. Esta revisión intenta mostrar los últimos avances sobre el rol de la visfatina y las principales adipocitoquinas en las patologías cardiovasculares y el síndrome metabólico. |
disciplina_str_mv |
Ciencias médicas |
autor_str_mv |
Miatello, Roberto Rodríguez Lanzi, María Cecilia Vazquez-Prieto, Marcela Alejandra |
object_type_str_mv |
Textual: Revistas |
id |
4178 |
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Artículo de Revista |
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article |
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Revista Médica Universitaria |
journal_title_str |
Revista Médica Universitaria |
journal_id_str |
r-1221 |
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Revista Médica Universitaria |
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Vol. 7, no. 1 |
journal_issue_str |
Vol. 7, no. 1 |
tipo_str |
textuales |
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Articulos |
title_full |
Adipocitoquinas y síndrome metabólico |
title_fullStr |
Adipocitoquinas y síndrome metabólico Adipocitoquinas y síndrome metabólico |
title_full_unstemmed |
Adipocitoquinas y síndrome metabólico Adipocitoquinas y síndrome metabólico |
description |
Cardiovascular disease is the leading cause of mortality in western countries.
Metabolic syndrome (MS), characterized by hyperlipidemia, hypertension, obesity and hyperglycemia, is a significant risk factor for cardiovascular disease. Visceral adipose tissue play a key role in the development of metabolic syndrome since this tissue secrets a variety of bioactive substances named adipokines or adipocytokines such as leptin, resistin, adiponectin, tumor necrosis factor alfa (TNFa), and visfatin. Visfatin has been described recently and its role in cardiovascular disease is controversial and has not yet been fully elucidated. Studies in human and animal experimental models suggest that visfatin would have a key role in the pathologies associates with cardiovascular disease. This review is focused in the role of visfatin as well as the main dipocytokines with cardiovascular disease and metabolic syndrome.
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dependencia_str_mv |
Facultad de Ciencias Médicas |
title |
Adipocitoquinas y síndrome metabólico |
spellingShingle |
Adipocitoquinas y síndrome metabólico Adipocitoquinas Adipocytokines Adiponectina Adipose tissue Cardiovascular diseases Diabetes Enfermedades cardiovasculares Factores de riesgo Leptina Mendoza (Argentina) Metabolic syndrome Obesidad Organización Mundial de la Salud Resistina Síndrome metabólico Tejido adiposo Visfatin Visfatina Miatello, Roberto Rodríguez Lanzi, María Cecilia Vazquez-Prieto, Marcela Alejandra |
topic |
Adipocitoquinas Adipocytokines Adiponectina Adipose tissue Cardiovascular diseases Diabetes Enfermedades cardiovasculares Factores de riesgo Leptina Mendoza (Argentina) Metabolic syndrome Obesidad Organización Mundial de la Salud Resistina Síndrome metabólico Tejido adiposo Visfatin Visfatina |
topic_facet |
Adipocitoquinas Adipocytokines Adiponectina Adipose tissue Cardiovascular diseases Diabetes Enfermedades cardiovasculares Factores de riesgo Leptina Mendoza (Argentina) Metabolic syndrome Obesidad Organización Mundial de la Salud Resistina Síndrome metabólico Tejido adiposo Visfatin Visfatina |
author |
Miatello, Roberto Rodríguez Lanzi, María Cecilia Vazquez-Prieto, Marcela Alejandra |
author_facet |
Miatello, Roberto Rodríguez Lanzi, María Cecilia Vazquez-Prieto, Marcela Alejandra |
title_sort |
Adipocitoquinas y síndrome metabólico |
title_short |
Adipocitoquinas y síndrome metabólico |
url |
https://bdigital.uncu.edu.ar/fichas.php?idobjeto=4178 |
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3 |
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Biblioteca Digital |
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Biblioteca Digital |
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Artículo de Revista |
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Sistema Integrado de Documentación |
indexed_str |
2023-04-25 00:38 |
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1764120320055181312 |